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Anna Stincone

Modeling Escherichia coli acid stress response:
I am interested in finding new regulators that could allow the bacterium to survive to acid stress conditions. In E. coli different Acid Stress Response Systems help the cells to tolerate acid stress and for some of them the mechanisms are already known. However, nothing is known about hypothetical interactions between these systems. With the use of the microarray technology I was able to collect data from time course experiments in acid stress conditions. The use of bioinformatic tools is important for the interpretation of big amounts of data from microarrays experiments but also for the creation of new biological models, which can be validated by experimental approaches