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Kim Clarke

Projects/Interests Aging and Frailty Frailty is characterised by a plethora of symptoms such as low functional reserve, decreased immune response leading to a higher susceptibility to disease, bad moods, osteoporosis and loss of muscle strength. We are asking the question, to what degree do a sedentary lifestyle, and increased levels of factors such as inflammation, CMV infection and mental stress have an effect on the prevelance and progression rate of frailty? My role as a bioinformatician will primarily be the analysis and interpretation of DNA microarrays done using muscle biopsies from physically active and sedentary aged individuals. Angiogenesis